Hemp Wellpure features phytocannabinoids & terpenes in a base of hemp extract and MaxSimil.
It is formulated to provide premium support for modulation of the endocannabinoid system.*
Phytocannabinoids and Terpenes the potential physiological and pathological impact of modulating the endocannabinoid system has been the focus of many studies that have helped elicit the health benefits of phytocannabinoids. For example, in a randomized, placebo controlled, double-blind study, overweight but otherwise healthy subjects (N = 65) ingested hemp oil extract containing 15 mg of phytocannabinoids for six weeks while following normal dietary and exercise measures. Outcome variables were broad and included changes in a 14-item panel of psychometric parameters, stress resilience, body composition, heart rate variability, plasma chromogranin A, and other general markers of health. In addition to tolerating the extract well, the test group showed a statistically significant improvement in blood lipid profile and reported better psychometric measures of perceived sleep, stress response, and perceived life pleasure compared to placebo.*
Terpenes are a class of compounds that give numerous plants and natural substances their distinct aroma and flavor. They are linked to cannabinoids through a shared precursor molecule. The hemp plant naturally contains over 200 terpene-like compounds, including beta-caryophyllene, myrcene, d-limonene, alpha-pinene, linalool, and terpineol, of which some have been studied for specific physiological functions. The synergistic interactions between phytocannabinoids and terpenes appear to enhance biological activity, a phenomenon that has been described in the literature as the “entourage effect.” Researchers who have studied the entourage effect between phytocannabinoids and terpenoids suggest a potential for targeting specific therapeutic products based on this synergy, but additional research is needed to fully understand and confirm these effects.*
Fish Oil Matrix the premium natural emulsifier delivery matrix in Hemp Wellpure is MaxSimil®, an IFOS five-star certified esterified fish oil that contains omega-3 polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).
Studies sponsored by the manufacturer of MaxSimil have demonstrated its enhanced bioavailability compared to other forms of omega-3 fatty acids. In a randomized, double-blind, crossover, controlled clinical trial, subjects (N = 20) received single doses of MaxSimil or an ethyl ester form. Plasma concentration of DHA was 2.5 times higher and EPA was 3 times higher in subjects receiving MaxSimil.*
Docosahexaenoic acid is an essential structural component of the central nervous system, and EPA plays a role in supporting healthy cardiac and circulatory systems. PUFAs also act as precursors to endocannabinoids. Studies have suggested a PUFA-rich diet is important for proper functioning of the ECS and could improve endocannabinoid signaling by reversing phospholipid fatty acid composition.*